颅内动脉瘤形态学和血流动力学研究进展

子立 蔡(承德医学院附属医院神经外科，中国)
杰 孟(承德医学院附属医院神经外科，中国)
继伟 张(承德医学院附属医院神经外科，中国)
淼 于(承德医学院附属医院神经外科，中国)

摘要

颅内动脉瘤是指颅内血管壁的病理性扩张，具有较高的破裂风险，同时颅内动脉瘤破裂也是造成自发性蛛网膜下腔出血（ SAH）的首要病因。动脉瘤破裂导致的蛛网膜下腔出血具有发病率高、死亡率高、预后差等特点，是当今社会严重危害人类健康的脑血管疾病之一。随着现代医学的发展，诊断动脉瘤的同时还能获取动脉瘤的形态学参数，这些参数对于预测动脉瘤破裂及治疗预后有重大作用，可以为临床医师提供最佳诊疗方案，缓解患者及其家庭乃至社会的伤痛。

关键词

颅内动脉瘤；形态学；血流动力学

参考

Dhar S, Tremmel M, Mocco J, et al. Morphology parameters for

intracranial aneurysm rupture risk assessment. Neurosurgery. 2008

Aug;63(2):185-96; discussion 196-197.

Wiebers DO, Whisnant JP, Huston J 3rd, et al.Unruptured

intracranial aneurysms:natural history, clinical outcome,

and risks of surgical and endovascular treatment[J].

Lancet,2003,362(9378):103-110．

唐晓宇,文立利,吴琪,等.尺寸比及子囊形成对颅内镜像动脉瘤破

裂的影响[J].河北医科大学学报,2023,44(2):167-172.

王冠宇,郭腾云,王舒楠,等.颅内小型动脉瘤破裂危险因素分析

[J].实用临床医药杂志,2021,25(11):1-3.

沈健,周海航,郁龚杰等.颅内动脉瘤形态学及血流动力学特征预

测破裂风险的临床意义[J].心电与循环,2022,41(3):272-274+283.

Lv N, Feng Z, Wang C, et al. Morphological risk factors for rupture

of Small (＜7 mm) posterior communicating artery aneurysms[J].

World Neurosurg,2016(87):311-315.

Elsharkawy A, Lehečka M, Niemelä M, et al. Anatomic risk factors

for middle cerebral artery aneurysm rupture: computed tomography

angiography study of 1009 consecutive patients. Neurosurgery.

,73(5):825-837.

黎峻,裴景春,杨淋,等.老年前循环小动脉瘤破裂危险因素分析

[J].老年医学与保健,2023,29(1):105-110+116.

杨利超,赵中甫,胡国超.动脉瘤形态、血流动力学和微小RNA

对颅内动脉瘤术中破裂的影响及预测价值[J].临床神经病学杂

志,2022,35(4):269-274.

闫薇,程慧冉,牛江涛.显微夹闭术与介入栓塞术治疗颅内动脉瘤

的效果及预后不良危险因素分析[J].医药论坛杂志,2023,44(13):

-69.

TREMMEL M,DHAR S,LEVY E I, et al.Influence of intracranial

aneurysm-to - parent vessel size ratio on hemodynamics and

implication for rupture : Results from a virtual experimental study

[J].Neurosurgery,2009,64(4):622-630.

Wang GX , Liu J , Chen YQ , et al. Morphological characteristics

associated with the rupture risk of mirror posterior communicating

artery aneurysms [J]. Neurointerv Surg,2018,10(10):995-998.

Kang H,Ji W,Qian Z, et al. Aneurysm characteristics associated

with the rupture risk of intracranial aneurysms : a self - controlled

study [J].PLoS One, 2015,10(11):e0142330.

Zhang Y, Jing L, Liu J, Li C, Fan J, Wang S, Li H, Yang X. Clinical,

morphological, and hemodynamic independent characteristic

factors for rupture of posterior communicating artery aneurysms. J

Neurointerv Surg, 2016,8(8):808-812.

吴磊,沈龙山,朱晶洁,等.颅内动脉瘤破裂风险评估中CTA的

有效性及形态学特征分析[J].蚌埠医学院学报,2020,45(9):

-1265.

HIGA T， UJIIE H， KATO K， et al． Basilar artery trunk saccular

aneurysms:morphological characteristics and management[J].

Neurosurg Ｒev, 2009,32(2):181-191．

DOI: http://dx.doi.org/10.12345/yzlcyxzz.v6i12.14897