血清sTREM-1联合IL-6对脓毒症患儿预后的评估价值

祎 刘(承德医学院附属医院，中国)
玉子 金(承德医学院附属医院，中国)
小青 敬(承德医学院附属医院，中国)

摘要

目的：研究可溶性髓样细胞触发受体-1（sTREM-1）联合白细胞介素-6（IL-6）对脓毒症患儿预后的评估价值。方法：选取承德医学院附属医院2021年9月—2023年9月PICU收治的58例脓毒症患儿，根据28d存活情况分为存活组42例和死亡组16例。检测患儿入院24h内血清sTREM-1、IL-6水平。Spearman相关性分析sTREM-1、IL-6与小儿危重症评分（PCIS）的相关性。通过ROC分析研究sTREM-1、IL-6以及联合检测在脓毒症患儿预后评估中的效能。结果：与生存组相比，死亡组的sTREM-1和IL-6水平显著升高（P＜0.05）。Spearman相关性分析得出sTREM-1及IL-6水平与PCIS均具有负相关性（P＜0.05）。ROC曲线显示sTREM-1联合IL-6评估脓毒症患儿不良预后的AUC为0.826。结论：sTREM-1和IL-6联合检测对脓毒症患儿预后评估具有较高效能。

关键词

可溶性髓样细胞触发受体-1；白细胞介素-6；脓毒症；预后

参考

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v7i3.16224