烧伤创面感染的危险因素及其最新研究进展

卓璐 师(青海大学附属医院，中国)
生武 晁(青海大学附属医院，中国)

摘要

烧伤创面感染是烧伤患者最常见的并发症之一，也是导致患者死亡的主要原因。论文综述了烧伤创面感染的危险因素及其最新研究进展。危险因素涵盖了创面深度与面积、年龄和基础健康状况、免疫抑制药物以及环境因素等。针对这些危险因素采取综合性的管理策略，包括及时的早期干预、适当的抗生素使用、严格的感染控制措施和优化患者的营养和医疗条件等。精准医疗、新型抗微生物药物、生物疗法，烧伤单位设计等领域的应用，为烧伤创面感染的管理提供了新的思路和方法。论文旨在提高临床医生对烧伤创面感染的认识，并为烧伤患者治疗和护理烧伤患者提供参考。

关键词

烧伤创面感染；危险因素；研究进展；管理策略

参考

Golubkova A A, Kutlaeva Y Y, Bagin V A. Features of nosocomial infections in patients with severe burn injury[J].Epidemiology and Infectious Diseases, 2021,26(5):214-223.

Lazarescu A-L, Grosu-Bularda A, Andrei M-C, et al. Burn infections characteristics: A review[J]. 2021,16(1):32-41.

Yolbaş İ, Tekin R, Kelekçi S, et al. Common pathogens isolated from burn wounds and their antibiotic resistance patterns; Yanık yaralarından izole edilen patojenler ve antibiyotik direnç durumları[J]. 2013.

Khudr M S, Ameen M K, Mahdi B M. Wound Infection Rates and the Results of Antibiotic Susceptibility Tests in Severely Burned Patients[J]. Medicine Science International Medical Journal, 2015,4(2):2165-2171.

Hamzaoui N E, Barguigua A, Larouz S, et al.Epidemiology of burn wound bacterial infections at a Meknes hospital, Morocco[J].new microbes and new infections, 2020,38:100764-100764.

Zhou S, Xiao S, Wang X, et al. Risk Factors and Pathogens of Wound Infection in Burn Inpatients from East China[J]. Antibiotics, 2023.

Ladhani H A, Yowler C J, Claridge J A. Burn Wound Colonization, Infection, and Sepsis[J]. Surgical Infections, 2021,22 (1):44-48.

Sun Y, Tang H, Wu T, et al. Burn-and Trauma-Associated Pulmonary Infection: Springer, Singapore, 2020:103-138.

Głowacka A, Baczyk G, Ulatowska A. Prevention of infection, effective control and treatment of infected burn wounds–the role of a nurse in an interdisciplinary team Zapobieganie zakażeniom, skuteczna kontrola i leczenie zakażonych ran oparzeniowych-rola pielęgniarki w zespole interdysc[J]. 2017,66(4).

Ning F, Zhao X-Z, Bian J, et al. Large-area burns with pandrug-resistant Pseudomonas aeruginosa infection and respiratory failure[J]. Chinese Medical Journal, 2011,124(3):359-363.

Savetamal A.Infection in Elderly Burn Patients: What Do We Know?[J]. Surgical Infections, 2021,22(1):65-68.

Rani M, Schwacha M G. Aging and the pathogenic response to burn[J]. Aging and Disease,2012,3(2):71-180.

Yang C F, Min D H, Guo G H. Research advances on the prevention and treatment of burn infection in the elderly[J]. 2023,39(3):285-289.

Bootun R. Effects of immunosuppressive therapy on wound healing[J]. International Wound Journal,2013,10(1):98-104.

Gharegozloo B, Hassan Z M, Ardestani S K, et al. Effect of Immunomodulator Pyrimethamine and Cimetidine on Immunosuppression Induced by Burn Blister Fluid[J]. Iranian Journal of Allergy Asthma and Immunology, 2004,3(3):139-143.

Leypold T, Schäfer B, Beier J P. Measures for Preventing Infection in Burn Surgery[J].Surgical technology international, 2022,41.

Kelly E J, Oliver M A, Carney B C, et al.Infection and Burn Injury[J].European burn journal, 2022,3(1):165-179.

Sharma S, Datta P, Gupta V, et al. Characterization of Bacteriological Isolates from Patients and Environment Samples of Burn Ward: A Study from a Tertiary Care Hospital of India[J].Infectious disorders drug targets, 2021,21(2):238-242.

Choong E, Jurat D R, Sandeep B, et al. The impact of infection on length of stay in adult burns: A scoping review[J].Burns, 2024.

Lachiewicz A M, Hauck C G, Weber D J, et al. Bacterial Infections After Burn Injuries: Impact of Multidrug Resistance[J]. Clinical Infectious Diseases, 2017,65(12):2130-2136.

杨加保,毛建华,马雷,等.老年烧伤后感染病人的病原菌分布及相关危险因素分析[J].实用老年医学,2020,34(4):348-351.

刘薇,程翔,梁玉龙,等.不同烧伤面积患者创面感染病原菌分布及其耐药性[J].中国感染控制杂志,2022,21(1):30-36.

Putra O N, Saputro I D, Hidayatullah A Y N. A retrospective surveillance of the prophylactic antibiotics for debridement surgery in burn patients[J]. 2021,11(2):96-104.

Pruitt B A, Mcmanus A T, Kim S H, et al. Burn wound infections: Current status[J]. World Journal of Surgery, 1998,22(2):135-145.

Tekin R, Dal T, Bozkurt F, et al. Risk factors for nosocomial burn wound infection caused by multidrug resistant Acinetobacter baumannii[J]. Journal of Burn Care & Research, 2014,35(1).

Sahlabadi F, Zandi H, Mokhtari M, et al. The Effectiveness Evaluation of Current Disinfectants on Pathogens Isolated from Surface of Different Parts of Shahid Sadughi Accidents Burns Hospital in City of Yazd[J]. Journal of Environmental Health Engineering, 2016,3(2):93-101.

Thompson M. The Nursing Effect of Different Dressings on Local Small Area Burn Wound[J].护理学,2022,11(2):279-284.

Alinejad F, Momeni M, Fatemi M J, et al. Comparing the effect of two types of silver nano-crystalline dressings (acticoat and agcoat) in the treatment of full thickness burn wound[J]. Iranian journal of microbiology2018,10(6):378-384.

Lawrence J C.Dressings and wound infection[J]. American Journal of Surgery, 1994,167(1).

Kour A, Jaglan S, Sharma S K, et al. A new strategy to treat Pseudomonas aeruginosa infected burn wounds: Antimicrobial cocktails as potent topical therapy[J]. Medical Hypotheses, 2023.

Haidari H, Amsalu A, Vasilev K, et al. An on-demand antibacterial hydrogel for precise and rapid elimination of bacterial infection in a murine partial thickness scald burn wound[J]. Applied Materials Today, 2024.

Hemmati J, Azizi M, Asghari B, et al. Multidrug-Resistant Pathogens in Burn Wound, Prevention, Diagnosis, and Therapeutic Approaches[J]. Conventional Antimicrobials and Nanoparticles, 2023.

Mahmoudi H, Pourhajibagher M, Chiniforush N, et al. Antimicrobial photodynamic therapy: modern technology in the treatment of wound infections in patients with burns[J]. Journal of Wound Care,2023,32(4).

Yahalom J, De Freitas D R J, Ofri A, et al. Antimicrobial photodynamic therapy: modern technology in the treatment of wound infections in patients with burns[J]. Journal of Wound Care, 2023,32(S4).

DOI: http://dx.doi.org/10.12345/yzlcyxzz.v7i9.21184