机械灌注在肝移植中的研究进展

广艺 朱(桂林医学院，中国)
煦勇 孙(广西医科大学第二附属医院，中国)

摘要

肝移植是治疗终末期肝病最有效的手段。供体器官短缺问题日趋严重，越来越多的扩大标准供体供肝被应用于临床肝移植。随之而来的一系列问题，对器官保存和修复技术提出了更高的要求。机械灌注可修复边缘供肝，减轻缺血-再灌注损伤，促进移植肝功能的恢复，降低术后并发症的风险。一系列临床研究已经初步证明了其安全性和有效性，但要广泛应用于临床，还需面临费用昂贵、操作复杂、灌注参数设置等难题。论文针对应用于肝移植的不同类型机械灌注技术进行综述。

关键词

肝移植；机械灌注；器官保存；灌注液；低温机械灌注；中温机械灌注；亚常温机械灌注；常温机械灌注

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DOI: http://dx.doi.org/10.26549/yzlcyxzz.v3i8.6242