咽喉反流与咽喉部疾病相关性研究进展

体强 黄(承德医学院附属医院，中国)
淑君 张(承德医学院附属医院，中国)

摘要

咽喉反流病（LPR，全称为喉咽反流）描述的是胃内物质逆流至食管上端括约肌以上区域，涵盖咽部、喉部、鼻腔、中耳乃至气管与支气管等部位的状况。长期存在的咽喉反流（LPR）能够直接或间接地诱发上消化道及呼吸道的炎性反应，最终诱发咽喉反流病（LPRD）。此病症候繁复多变，涵盖咽喉部频繁清嗓的动作、有如异物梗阻感、声音嘶哑、持续发声感觉疲劳、咽喉部位疼痛不适、呼吸时感觉不畅、久咳不愈以及喉部可能出现痉挛等症状。当前，咽喉反流在临床上的表现及体征颇为复杂而且会随病程变化，缺乏具有特异性的指征，因此在国内外尚未形成统一明确的诊断标准。导致咽喉部位受损的咽喉反流因素纷繁复杂，且其诱发咽喉疾病的机理也各有千秋。本文汇总了咽喉反流诊断的主要手段，并探讨了其与咽喉疾病之间的密切联系，旨在为咽喉反流相关疾病的诊断与治疗开辟新的思路。

关键词

咽喉反流；诊断；机制；研究进展；文献综述

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v7i12.22898