Cg A 在脓毒症诱导的器官功能障碍中的研究进展

伟 党(内蒙古医科大学内蒙古临床医学院，中国;)
俊利 李(内蒙古自治区人民医院儿科，中国;)

摘要

脓毒症是由疑似或确诊感染引起的全身性炎症反应，可导致多脏器功能衰竭，具有较高的死亡率。脓毒症诱发器官衰竭的机制极为复杂，涵盖了免疫反应异常、血流动力学显著改变以及内皮功能严重损伤等多个方面。嗜铬粒蛋白A（Chromogranin A，Cg A）是一种神经内分泌细胞分泌的糖蛋白，参与调节免疫、血管舒缩等功能。近年来，研究发现与脓毒症的发生和器官损伤密切相关。本文旨在综述Cg A在脓毒症诱导的器官功能障碍中的研究进展，探讨其潜在的作用机制，并总结其在临床诊断与治疗中的应用前景。

关键词

脓毒症；嗜铬粒蛋白A；器官功能障碍

参考

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v8i1.23404