IL-15、S1P、TGF-β1 在子宫内膜异位症的表达及意义
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【1】 Zubrzycka, A., Migdalska-Sęk, M., Jędrzejczyk, S. & Brzeziańska-Lasota, E. The Expression of TGF-β1, SMAD3, ILK and miRNA-21 in the Ectopic and Eutopic Endometrium of Women with Endometriosis. Int J Mol Sci 24, 2453 (2023).【2】 Vissers, G., Giacomozzi, M., Verdurmen, W., Peek, R. & Nap, A. The role of fibrosis in endometriosis: a systematic review. Human Reproduction Update 30, 706 (2024).【3】 Aliabad, R. A., Hassanpour, K. & Norooznezhad, A. H. Cannabidiol as a possible treatment for endometriosis through suppression of inflammation and angiogenesis. Immunity, Inflammation and Disease 12, e1370 (2024).【4】 Mitranovici, M.-I. et al. Shared Pathogenic and Therapeutic Characteristics of Endometriosis, Adenomyosis, and Endometrial Cancer: A Comprehensive Literature Review. Pharmaceuticals (Basel) 17, 311 (2024).【5】 Bernacchioni, C. et al. Sphingosine 1-phosphate receptors are dysregulated in endometriosis: possible implication in transforming growth factor β-induced fibrosis. Fertil Steril 115, 501–511 (2021).【6】 Garcia Garcia, J. M. et al. Endometriosis: Cellular and Molecular Mechanisms Leading to Fibrosis. Reprod Sci 30, 1453–1461 (2022).【7】 Effendi, K. Y. et al. Diagnostic Test of Transforming Growth Factor-Beta 1 (TGF-β1) in Menstrual Blood with Endometriosis. Obstet Gynecol Int 2023, 9970818 (2023).【8】 Soni, U. K. et al. A high level of TGF-B1 promotes endometriosis development via cell migration, adhesiveness, colonization, and invasiveness†. Biology of Reproduction 100, 917–938 (2019).【9】 Liu, Z., Yi, L., Du, M., Gong, G. & Zhu, Y. Overexpression of TGF-β enhances the migration and invasive ability of ectopic endometrial cells via ERK/MAPK signaling pathway. Exp Ther Med 17, 4457–4464 (2019).【10】 Feng, Y., Dong, H. & Tan, B. Endometriotic mesenchymal stem cells promote the fibrosis process of endometriosis through paracrine TGF-β1 mediated RASAL1 inhibition. J Obstet Gynaecol Res 50, 467–477 (2024).【11】 Guo, S. Cancer driver mutations in endometriosis: Variations on the major theme of fibrogenesis. Reprod Med Biol 17, 369–397 (2018).【12】 Shi, L. B. et al. Transforming growth factor beta1 from endometriomas promotes fibrosis in surrounding ovarian tissues via Smad2/3 signaling. Biol Reprod 97, 873–882 (2017).【13】 Paolo, A. D. et al. Pathogenic Role of the Sphingosine 1-Phosphate (S1P) Pathway in Common Gynecologic Disorders (GDs): A Possible Novel Therapeutic Target. International Journal of Molecular Sciences 23, 13538 (2022).【14】 Bernacchioni, C. et al. Sphingosine-1-phosphate receptor 3 is a non-hormonal target to counteract endometriosis-associated fibrosis. Fertil Steril 121, 631–641 (2024).【15】 Zhang, F. et al. Blocking sphingosine 1-phosphate receptor 1 with modulators reduces immune cells infiltration and alleviates endometriosis in mice. Reprod Biomed Online 47, 103304 (2023).【16】 Zhang, F. & Lu, Y. The Sphingosine 1-Phosphate Axis: an Emerging Therapeutic Opportunity for Endometriosis. Reprod Sci 1–20 (2023) doi:10.1007/s43032-023-01167-2.
DOI: http://dx.doi.org/10.12345/yzlcyxzz.v8i1.23411
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