The Antibacterial Properties of Silver Dressings and Their Application in Wound Healing

Jiawei Cao(Medical College, Pingdingshan University)
Jinxu Qi(Medical College, Pingdingshan University Henan Runling Pharmaceutical Co., LTD.)

Abstract

Silver-containing dressings have gained popularity in clinical applications due to their exceptional antibacterial properties and ability to enhance wound healing. These dressings primarily exert their antibacterial effects through the utilization of silver ions or nano-silver particles. The antimicrobial property of silver ions is a result of multiple mechanisms, with the most significant being the interaction between Ag or Ag⁺ and the bacterial cell wall, as well as the interaction between Ag⁺ and bacterial DNA or RNA, which inhibits replication and division. Silver-containing dressings can effectively reduce inflammation in wound tissue and expedite wound healing. The antibacterial and wound-healing promoting effects of these dressings are closely associated with the controlled release rate of silver ions. Consequently, developing novel silver-containing dressings that accurately regulate this release rate has become a prominent area of research interest. With broad prospects for application in wound care, silver-containing dressings are anticipated to offer innovative solutions for addressing numerous challenges encountered in clinical wound management.

Keywords

Silver-containing dressings; Antimicrobial; Wound healing; Release rate

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DOI: http://dx.doi.org/10.26549/jams.v7i2.21793