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含I型血小板结合蛋白基序的解聚蛋白样金属蛋白酶-5的研究进展

拓 杨(承德医学院附属医院心血管内科,中国)
虹 王(承德医学院附属医院心血管内科,中国)
立杰 柴(承德医学院附属医院心血管内科,中国)

摘要

Adamts5是ADAMTSs家族中的一员,该家族是一种新发现的一类依赖Zn2+分泌型金属蛋白酶。Adamts5目前在骨关节炎、心血管疾病、肿瘤等多种疾病中有着密切的关系。随着人类对Adamts5的逐步了解,推测Adamts5这个功能复杂的金属蛋白酶未来可在医学领域的疾病研究、药物治疗方面发挥强大的作用,论文将对其相关内容进行综述。

关键词

Adamts5;癌症;冠状动脉粥样硬化心脏病;肥胖;骨关节炎

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参考

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v5i2.11286

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