眼附属器 MALT 淋巴瘤生物标志物的研究进展

帅 姜(承德医学院附属医院眼科，中国)
志军 董(承德医学院附属医院眼科，中国)
微莉 董(承德医学院附属医院眼科，中国)

摘要

眼附属器淋巴瘤最常见的类型是MALT淋巴瘤，其恶性程度普遍较低，但缺乏特异的临床表现，同时具有复发、扩散及从低级别淋巴瘤转化为高级别侵袭性淋巴瘤可能等特点，这些特点普遍导致较差的预后，早期准确识别、诊断及治疗是患者得到良好预后的有效手段。因此，进一步研究寻找眼附属器MALT淋巴瘤的生物标志物和发病机制尤为重要。论文将聚焦眼附属器MALT淋巴瘤生物标志物的研究进展，对既往研究成果从突变基因、染色体异常、炎症抗原刺激、信号传导相关因子、癌基因及细胞周期相关因子几方面对生物标志物作一综述。

关键词

眼附属器黏膜相关淋巴组织淋巴瘤；生物标志物；进展

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v6i1.12315