巨噬细胞极化与良性前列腺增生的关系研究进展

朋飞 马(河北省人民医院泌尿外科，中国)
家瑞 崔(河北省人民医院泌尿外科，中国)
光磊 赵(河北省人民医院泌尿外科，中国)
守宾 李(河北省人民医院泌尿外科，中国)

摘要

巨噬细胞可根据周围微环境的变化极化为M1型和M2型，巨噬细胞的极化通过调控JAK/STAT、TGF-β/Smads、PPARγ和TLR4等信号通路，影响炎性微环境，起到一定的效力前列腺增生的发生发展中。论文针对巨噬细胞极化与前列腺增生发生发展的关系进行综述，为BPH防治提供理论指导。

关键词

良性前列腺增生；巨噬细胞；巨噬细胞极化方向

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v6i9.13811