糖代谢紊乱在脓毒症中的研究进展

秀瑞 孙(承德医学院附属医院，中国)
玉子 金(承德医学院附属医院，中国)
小青 敬(承德医学院附属医院，中国)

摘要

脓毒症（sepsis）是宿主对感染的免疫反应失调导致的危及生命的器官功能障碍，是全球范围内导致死亡的主要疾病之一。脓毒症发病机制复杂，早期伴随促炎抗炎机制的出现，会导致过度炎症和免疫抑制，甚至出现长期的代谢紊乱。脓毒症时发生糖代谢紊乱会出现高血糖、低血糖和血糖变异性增加。脓毒症患者糖代谢紊乱发生率高，与疾病严重程度、病死率及并发症的增加密切相关。因此，研究脓毒症时糖代谢紊乱的机制及治疗对糖代谢紊乱逆转十分重要。

关键词

糖代谢；高血糖；低血糖；血糖变异度；脓毒症

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v7i3.16226