脓毒症生物标志物研究进展

腾飞 王(承德医学院附属医院，中国)
立伟 滑(承德医学院附属医院，中国)

摘要

脓毒症是重症医学科的常见病，由于其死亡率高、发病率高及经济负担大等特点，同时也是危重症之一。目前脓毒症的临床诊断仍缺乏金标准，临床上尚未有一个理想的生物标志物可以诊断脓毒症。一个理想的生物标志物应该是有效的、廉价的、可广泛获得的和结果是快速可用的，通过早期监测脓毒症患者的生物标志物及动态改变，实施干预，可以改善临床结局。论文主要从降钙素原、白介素-6、C反应蛋白、肝素结合蛋白等感染相关的生物标志物及乳酸、后负荷相关心脏做功、中心静脉-动脉二氧化碳分压差等器官功能障碍的生物学标志物两方面进行主要综述，并且简要概述了几种潜在的新型的生物学标志物，供临床参考。

关键词

脓毒症；生物标志物；诊断；预后

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v7i2.16323