维生素 A 与新生儿免疫的研究进展

亦芳 郭(承德医学院附属医院，中国)
启立 周(承德医学院附属医院，中国)

摘要

维生素A（VA）是脂溶性维生素，对于维持视力、促进生长发育、保护体内上皮和黏液的完整性、调节骨骼代谢等方面有非常重要的作用。新生儿这一特殊群体，普遍存在维生素A缺乏，且其免疫系统发育尚不成熟，抵抗力低下，尤其体液免疫功能尚处于早期阶段，极其容易出现肺炎、败血症、新生儿坏死性小肠结肠炎等感染相关疾病，且死亡率低、预后性差，这成为困扰新生儿医务人员的难题。近年来，对于VA与感染相关机制的研究逐渐深入、完善，论文针对目前中国和其他国家对VA水平与免疫机制的研究进行总结。

关键词

维生素A；维生素A缺乏症（VAD）；固有免疫；适应性免疫；新生儿

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v7i2.16342