胶原蛋白对于糖尿病创面的研究进展

阳 杜(青海大学附属医院，中国)
毅 李(青海大学附属医院，中国)

摘要

糖尿病是一种慢性代谢性疾病，主要特点是血糖水平长期升高。糖尿病患者常常面临创面愈合困难的问题，这是由于高血糖环境导致的血管病变、神经损伤和免疫功能下降所致。近年来，有关用于糖尿病伤口愈合的胶原蛋白的研究取得了重大进展，重点是开发基于胶原蛋白的创新材料及其作用机制。这些进展旨在应对糖尿病伤口带来的复杂挑战，如长期炎症、血管生成受损和基质金属蛋白酶活性过高。论文将综述胶原蛋白在糖尿病创面愈合中的研究进展，探讨其作用机制和应用前景。

关键词

胶原蛋白；糖尿病创面；胶原蛋白敷料

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v7i9.21186