肠道微生物与恶性肿瘤关系的研究进展

丽娜 施(青海大学附属医院，中国;青海大学研究生院，中国)

摘要

近年来随着科学技术的不断发展，人们已经越来越意识到肠道微生物的重要性，肠道微生物的生态失调，会导致各种病理状况的发生，包括肥胖、糖尿病、神经退行性疾病以及癌症。越来越多的研究揭示了微生物群与癌症之间的联系，肠道微生物群的生态失调通过诱导炎症、促进细胞生长和增殖、削弱免疫监视以及改变宿主的食物和药物代谢或其他生化功能而与肿瘤发生有关。论文主要针对肠道微生物与肿瘤的发生发展、治疗疗效相关性进行讨论，以寻找微生物群在肿瘤诊断、治疗和预防等方面的潜在价值。

关键词

肠道微生物；肺癌；胃肠道肿瘤；宫颈癌；发生发展；预后

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v7i10.21655