合并桥本氏甲状腺炎对甲状腺癌发生发展影响的研究进展

莹 李(青海大学研究生院，中国)
海宁 赵(青海大学附属医院乳甲肿瘤外科，中国)

摘要

甲状腺癌（thyroid carcinoma，TC），作为内分泌系统中最常见的恶性肿瘤，其主要亚型为甲状腺乳头状癌（papillary thyroid carcinoma，PTC）。PTC构成了甲状腺癌病例中的绝大多数。桥本甲状腺炎（HT）是一种常见的自身免疫性疾病，其特点在于免疫系统对甲状腺组织产生病理性激活。关于甲状腺乳头状癌与桥本甲状腺炎发病率的上升，二者是否源于相似的致病因素，抑或是存在某种相互作用机制，仍是学界争论的热点问题。鉴于目前对于这两者关联性的具体研究成果存在显著差异，本研究旨在通过回顾甲状腺自身免疫疾病与甲状腺癌的相关文献，探究两者之间可能存在的内在联系。

关键词

甲状腺乳头状癌；桥本甲状腺炎；发病机制

参考

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v7i10.21664