术后谵妄（POD）的病理生理机制与生物标志物研究进展

小彤 王(承德医学院，中国)
铁莉 于(承德医学院，中国)

摘要

术后谵妄是术后急性脑功能紊乱的表现，多见于老年患者，典型症状表现为意识混乱、注意力不集中、定向力障碍或情绪波动，术后谵妄的发生与高龄、基础疾病、手术创伤、麻醉药物等因素有关，需采取综合预防和干预。关于术后谵妄的病理生理机制以及发病机制无法明确，缺乏有效的生物学指标和临床指标，因此影响了患者术后谵妄的早期诊断和预防。本文针对术后谵妄的病理生理机制与生物标志物进行研究，为临床预防术后谵妄提供有力的依据。

关键词

术后谵妄；病理生理机制；生物标志物；研究进展

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v8i6.29028