骨微观结构及力学性能之间的构效关系

春燕 田(重庆健康职业学院，中国)
毅 刘(重庆健康职业学院，中国)

摘要

骨骼作为天然生物复合材料，力学性能与微观结构紧密相关。本研究结合实验与数值模拟，探究牛骨力学特性与微观结构响应机制：通过压缩、拉伸、弯曲实验获取力学参数，结合高分辨率 Micro CT 构建三维有限元模型；发现哈弗氏管等孔隙结构载荷下产生应力集中，直接影响骨力学行为与断裂特征，数值模拟显示损伤始于孔隙边缘并沿管道网络扩展。该研究多尺度揭示骨组织结构 - 性能关系，为骨修复治疗、仿生支架设计及骨替代材料优化提供理论依据。

关键词

生物力学；Micro CT；骨微观结构；骨修复

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v9i1.35867