局部进展期食管癌新辅助治疗进展
摘要
近年来,越来越多的研究表明新辅助治疗联合手术能明显改善局部进展期食管癌病人的5年生存率,包括新辅助放疗、化疗及同步放化疗。通过术前辅助治疗可能达到肿瘤术前降期,提高肿瘤的完全切除率( R0),降低局部复发率,最终使患者达到生存获益的目的。自从新辅助治疗的概念提出以来,但是也有多项研究显示,术前辅助治疗联合手术较传统单独手术方式的各种优势时,也存在提高并发症的风险,因而,这些研究结论的可推广性一直受到广泛质疑。本文对近年来局部进展期食管癌新辅助治疗的研究进展作一综述。
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DOI: http://dx.doi.org/10.26549/yzlcyxzz.v3i4.4040
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