二十碳五烯酸与妊娠糖尿病的研究进展

涛 姚(华北理工大学附属医院妇产科，中国)
景鹤 白(华北理工大学附属医院妇产科，中国)
欣瑜 刘(华北理工大学附属医院妇产科，中国)
芯 谢(华北理工大学附属医院妇产科，中国)
新宇 张(华北理工大学附属医院妇产科，中国)
军 邢(华北理工大学附属医院妇产科，中国)

摘要

妊娠期糖尿病目前属于常见妊娠期代谢紊乱综合征之一，严重影响母胎安全。近年来研究认为，母胎界面胎盘的低度炎症反应是诱发妊娠期胰岛素抵抗的原因，所以针对胎盘源性炎症的治疗极具治疗价值。最近十年，二十碳五烯酸作为一种多不饱和脂肪酸，因其具有抗炎、抗肿瘤等作用而得到人们的重视。因此，将其用于妊娠期糖尿病的治疗具有较高研究价值。

关键词

妊娠期糖尿病；Toll样受体-4；胰岛素抵抗；多不饱和脂肪酸　

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DOI: http://dx.doi.org/10.26549/yzlcyxzz.v3i6.5836