右美托咪定复合地氟醚麻醉对患儿术后苏醒的影响

正华 吴(南昌大学第一附属医院，中国)

摘要

目的：接受全身麻醉的患儿经常出现术后燥动。这项研究测试了在斜视手术的患儿中，使用小剂量右旋美托咪定输注，复合地氟醚麻醉，右美托咪定是否能降低麻醉后出现术后躁动（EA）的发生率。方法：总共接受了斜视手术的96名患儿。麻醉诱导采用芬太尼，异丙酚和罗库溴铵进行，麻醉维持吸入地氟醚。在手术过程中，DF组给患者输注0.2μg/（kg·h）-1右美托咪定，F组输注等容量的生理盐水。麻醉苏醒在PACU，每10分钟记录一次术后客观疼痛评分（OPS），术后躁动（EA）评分。结果：两组中DF组在到达苏醒室后的0、10和20分钟时，最大EA，最大OPS评分的均值显著低于F组（P<0.001）。DF组追加芬太尼的次数低于F组（P<0.001）。DF组中严重EA的发生率明显低于F组（12.8％对74.5％，P<0.001）。结论：在斜视手术的患儿中，术中小剂量输注右美托咪定和芬太尼可降低地氟醚麻醉后的术后躁动（EA）。

关键词

右美托咪定；术后躁动；地氟醚

参考

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v4i5.7720