简述肺癌中的独特代谢

馨予 闫(内蒙古医科大学，中国)
俊珍 高(内蒙古医科大学附属医院呼吸与危重症医学科，中国)

摘要

肺癌对人类健康危害极大，非小细胞肺癌是其最常见的分型。因肺癌本身起病隐匿，早期很难发现，70%~75%的肺癌患者在诊断时已为晚期，5年生存率只有20%，所以期望能有更多的方法来辅助早期诊断及大范围筛查。肿瘤细胞具有的独特代谢特点，即细胞内的微小变化即可引起代谢物的“延增效应”，利用肺部恶性肿瘤细胞的独特代谢，或可从中识别异常代谢物，帮助早期诊断及筛查，代谢组学之前受限于检测方法，随着检测技术的提高，代谢组学开始成为大家的焦点。论文就代谢组学的概述、样品、方法，肺癌患者与健康人相比的独特代谢做一个回顾，希望能辅助早期诊断并对肺癌患者的治疗及预后疗效起到一定作用。

关键词

肺癌；代谢组学；特异性代谢物

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v4i8.8524