口腔鳞状细胞癌相关LncRNA的功能机制

敬媛 项(内蒙古医科大学口腔医学院，中国)
杰 武(内蒙古自治区人民医院检验科，中国)
十 七(内蒙古医科大学附属医院口腔科，中国)

摘要

口腔鳞状细胞癌是头颈部最常见的鳞状细胞癌之一，其发生发展过程复杂，治疗方法主要为手术联合放疗、新辅助化疗、免疫治疗及靶向治疗，然而多年来口腔鳞状细胞癌的发病率和死亡率并没有明显改善。长链非编码RNA作为近年来的研究热点，已被证实通过多种途径和分子机制参与了肿瘤发展的各个阶段，在口腔鳞状细胞癌中的作用也尤为重要。论文对口腔鳞状细胞癌中几类主要的长链非编码RNA进行概述，以期寻找治疗靶点，为临床治疗提供新思路至关重要。

关键词

口腔鳞状细胞癌；长链非编码RNA；靶向治疗

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v4i9.8678