开放期刊系统

粘液在人体组织中的研究进展

培峰 贾(内蒙古医科大学,中国)
笑宇 高(内蒙古自治区人民医院,中国)
春梅 云(内蒙古自治区人民医院,中国)

摘要

粘液是一种复杂的稀水黏弹性分泌物,由柱状上皮中的粘液细胞合成和分泌,主要分布在胃肠道、眼、鼻、肺、宫颈和阴道等组织中。人体粘液具有可持续分泌的特点,主要由水、粘蛋白和脂质成分等组成。在人体正常生理状态下,粘液不断地分泌,并从粘膜表面脱落,形成一个持续更新的动态系统,从而发挥其作为屏障的保护作用,帮助人体清除有害物质,抵御病菌,润滑组织等,然而其作用在不同组织中也存在着差异,论文就粘液在不同组织中表达特征和作用进行综述。

关键词

粘液;粘蛋白;呼吸道粘液;消化道粘液;宫颈阴道粘液

全文:

PDF

参考

Andrianifahanana M, Moniaux N, Batra SK. Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases[J]. Biochimica et biophysica acta, 2006,1765(2):189-222.

Evans CM, Koo JS. Airway mucus: the good, the bad, the sticky[J]. Pharmacology & therapeutics, 2009,121(3):332-348.

TBansil R, Turner BS. The biology of mucus: Composition, synthesis and organization[J]. Adv Drug Deliv Rev, 2018,15(124):13-15.

Taherali F, Varum F, Basit AW. A slippery slope: On the origin, role and physiology of mucus[J]. Advanced drug delivery reviews, 2018(124):16-33.

Rogers DF. Airway mucus hypersecretion in asthma: an undervalued pathology[J]. Current opinion in pharmacology, 2004,4(3):241-250.

Rubin BK. Mucus, phlegm, and sputum in cystic fibrosis[J]. Respiratory care, 2009,54(6):726-732.

Sicard JF, Le Bihan G, Vogeleer P, et al. Interactions of intestinal bacteria with components of the intestinal mucus[J]. Frontiers in cellular and infection microbiology, 2017(7):387.

Johansson ME, Sjövall H, Hansson GC. The gastrointestinal mucus system in health and disease[J]. Nature reviews Gastroenterology & hepatology, 2013,10(6):352-361.

Vagios S, Mitchell CM. Mutual preservation: A review of interactions between cervicovaginal mucus and microbiota[J]. Frontiers in cellular and infection microbiology, 2021(11):676114.

Mall AS, Habte H, Mthembu Y, et al. Mucus and mucins: do they have a role in the inhibition of the human immunodeficiency virus[J]. Virology journal, 2017,14(1):192.

Pflugfelder SC, Stern ME. Biological functions of tear film[J]. Experimental eye research, 2020(197):108115.



DOI: http://dx.doi.org/10.12345/yzlcyxzz.v4i11.9298

Refbacks

  • 当前没有refback。
版权所有(c)2021 培峰 贾, 笑宇 高, 春梅 云 Creative Commons License
此作品已接受知识共享署名-非商业性使用 4.0国际许可协议的许可。
  • :+65-62233778 QQ:2249355960 :contact@s-p.sg