Nanotechnology-Based Strategies for Enhanced Radiotherapy Delivery and Tumor Targeting

Lucie E. Caru(Departments of Oncology and Pediatrics, Alberta Children's Hospital, University of Calgary, Cumming School of Medicine, Calgary, AB, Canada.)

Abstract

Radiotherapy is a cornerstone of cancer treatment, but its effectiveness can be limited by adverse effects on healthy tissues and insufficient tumor targeting. Nanotechnology-based approaches offer innovative solutions to enhance radiotherapy delivery and improve tumor targeting. This essay aims to explore the potential of nanotechnology in enhancing radiotherapy outcomes by discussing various strategies for precise radiation delivery, tumor-specific targeting, and synergistic combination therapies. It provides an overview of nanomaterials used in radiotherapy, such as nanoparticles, liposomes, and nanocarriers, and highlights their unique properties that facilitate improved drug delivery and image-guided radiation therapy. The essay also examines the challenges and future prospects of nanotechnology-based strategies in radiotherapy, including regulatory considerations and clinical translation.

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