Exploring the Potential of Viral Oncology in Cancer Immunotherapy: A Focus on Targeted Tumor Destruction

Pérez-Herrero E(University of Sheffield, Sheffield, UK)
Allavena P.(University of Sheffield, Sheffield, UK)

Abstract

Cancer immunotherapy has revolutionized cancer treatment by harnessing the power of the immune system to recognize and eliminate cancer cells. Viral oncology, a rapidly evolving field, offers exciting prospects for cancer immunotherapy through targeted tumor destruction. This essay aims to explore the potential of viral oncology in cancer immunotherapy, with a specific focus on leveraging viruses for precise and selective tumor eradication. It discusses the mechanisms underlying the tumor-specific immune response induced by oncolytic viruses, the strategies employed to enhance viral targeting and replication within tumors, and the modulation of the immune system to potentiate antitumor immunity. Moreover, the essay examines the challenges and future directions of viral oncology-based cancer immunotherapy, including safety considerations, combination therapies, and personalized medicine approaches.

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